Prof. Md. Lokman Hakim Choudhury

Prof. Md. Lokman Hakim Choudhury
Professor
Ph.D, IIT Guwahati
Ph: +91-6115-233 038
lokman[*AT]iitp.ac.in
https://scholar.google.co.in/citations?hl=en&user=wX-VDiIAAAAJ&pagesize=100&view_op=list_works&sortby=pubdate
Research Areas
  • Green Synthesis, multicomponent reactions (MCRs), organocatalysis, design and development of light mediated reactions, synthesis and functionalization of heterocycles and multicomponent polymerization.
Students
Sr. No. Photo Area of Reasearch Degree
1
Vidya Kumari (Ph.D student)
2
Danish Ali (Ph.D student)
3
Nurabul Mondal (Ph.D student)
Former Students
Sr. No. Photo Area of Reasearch Current Position
1
Asim Jana (Ph.D., IITP, 2022)
2
Anoop K. Panday (Ph.D., IITP, 2021)
3
Richa Mishra (Ph.D., IITP, 2019)
4
Sheikh Karamthulla (Ph.D., IITP, 2016)
5
Md. Nasim Khan (Ph.D., IITP, 2016)
6
Suman Pal (Ph.D., IITP, 2014)
7
Prabhas Bhowmick (Ph.D, IITP, 2023)
Current Sponsored Projects
Sr. No. Title Principal Investigator Co-Principal Investigator Duration Sponsoring Agency Cost Status
1 Design and Development of Visible Light-Driven Multicomponent Reactions Using Organophotocatalysis. Prof. Md. Lokman H. Choudhury SERB, DST, Govt. of India Ongoing
2 Exploration of Multicomponent Reactions (MCRs) Towards Green Synthesis of Novel Functionalized & Sequence Regulated Macromolecules Dr. Md.Lokman H. Choudhury SERB, DST, Govt. of India Completed
3 Diversity oriented synthesis of privileged heterocycles & highly functionalized carbocycles by multicomponent reactions (MCRs) Dr. Md.Lokman H. Choudhury SERB,DST, Govt.of India Completed
Professional Experience
  • Lecturer/Asst. Professor in Chemistry, School of Technology, North-Eastern Hill University, Shillong (Jan 2007-Feb 2009) Royal Society Incoming Postdoctoral Fellow, (The University of Manchester, UK, Aug-2007-Feb-2008) Assistant Professor (Department of Chemistry, IIT Patna, Feb 2009- Dec 2015) Associate Professor (Department of Chemistry, IIT Patna, Dec 2015- Feb 2022) Professor (Department of Chemistry, IIT Patna, Feb 2022- till now)
Administrative Experience
  • HoD, Department of Chemistry, Nov 2021-March 2023. Head, Sophisticated Analytical Instrument Facility (SAIF) (April 2016-March 2019, Nov 2021- March 2023) Coordinator of Department (CoD), Dept. of Chemistry, (July 2011 to Dec 2013)
Publications / Journals / Conferences
    • Synthesis of Highly Fluorescent Polycyclic Carbazole Fused Thiazoles by Sunlight Assisted Photocyclization. Prabhas Bhaumick,a Nurabul Mondala and Lokman H. Choudhury (Manuscript under communication)
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    • Synthesis of Selenocyanates and Selenoethers of Amino Pyrazoles and Amino Uracils by In Situ Triselenium Dicyanide from Malononitrile and Selenium Dioxide. Danish Ali, Nurabul Mondal, Anoop Kumar Panda, Lokman H. Choudhury, ACS Omega, 2023, https://doi.org/10.1021/acsomega.3c02769.
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    • HFIP-mediated Multicomponent Reactions for the Synthesis of Fluorescent Quinoline-fused Pyrroles, Rohit Kumar, Swadhin S. Acharya, Prabhas Bhaumick, Tasneem Parvin, Lokman H. Choudhury, Tetrahedron, 2023, 132,133250, https://doi.org/10.1016/j.tet.2023.133250
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    • Metal-Free Synthesis of Pyrimidine and Naphthoquinone-Fused Pyrroles from Arylglyoxal-Based Domino Reactions. Anoop Kumar Panday, Danish Ali, Tasneem Parvin, Lokman H. Choudhury, ChemistrySelect, 2023, 8, e20230015. https://doi.org/10.1002/slct.202300158.
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    • Multicomponent Synthesis of Fluorescent Thiazole-Indole Hybrids and Thiazole Based Novel Polymers. Prabhas Bhaumick, Rohit Kumar, Swadhin Swaraj Acharya, Tasneem Parvin, Lokman H. Choudhury, The Journal of Organic Chemistry, 2022, 87, 11399–11413. https://doi.org/10.1021/acs.joc.2c00922
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    • Sc(OTf)3-Mediated One-Pot Synthesis of Coumarin-Fused Furans: A Thiol-Dependent Reaction for the Easy Access of 2-Phenyl-4H-furo[3,2-c]chromen-4-ones. Asim Jana, Danish Ali, Prabhas Bhaumick, Lokman H. Choudhury, The Journal of Organic Chemistry, 2022, https://doi.org/10.1021/acs.joc.2c00353.
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    • Visible Light-Mediated C(sp2)–H Selenylation of Amino Pyrazole and Amino Uracils in the Presence of Rose Bengal as an Organophotocatalyst. Danish Ali, Tasneem Parvin, Lokman H. Choudhury, The Journal of Organic Chemistry 2022, 87, 1230-1239. https://doi.org/10.1021/acs.joc.1c02565
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    • Iodine-Catalyzed Multicomponent Synthesis of Highly Fluorescent Pyrimidine-Linked Imidazopyridines. Swadhin Swaraj Acharya, Prabhas Bhaumick, Rohit Kumar, Lokman H. Choudhury, ACS Omega, 2022, https://doi.org/10.1021/acsomega.2c01332.
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    • Multicomponent click polymerization for the synthesis of coumarin containing 1, 4-polytriazoles and their application as dye adsorbent. Prabhas Bhaumick, Lokman H. Choudhury, Polymer, 2022, 243, 124580. https://doi.org/10.1016/j.polymer.2022.124580
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    • Synthesis of Pentacyclic Pyran Fused Pyrazolo Benzo[h]quinolines by Multicomponent Reaction and Their Photophysical Studies. Rahul Yadav, Darakshan, Prabhas Bhaumick, Lokman H. Choudhury, T Parvin, Chemistry Select, 2022, 7, e202104124.  https://doi.org/10.1002/slct.202104124
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    • A reversible and efficient probe for dual mode recognition of Al3+ and Cu2+ with logic gate behaviour: Crystal structure, theoretical and in-vivo bio-imaging investigations. Pranjalee Yadav, Rohit Kumar, S Srikrishna, Anoop Kumar Pandey, Lokman H. Choudhury, Chandan Upadhyay, Vinod P Singh, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 267, 120552. https://doi.org/10.1016/j.saa.2021.120552.
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    • Synthesis of styryl-linked fused dihydropyridines by catalyst-free multicomponent reactions. Rahul Yadav, Tasneem Parvin, Anoop Kumar Panday, Lokman H. Choudhury, Molecular Diversity, 2021, 25, 2161-2169. https://doi.org/10.1007/s11030-021-10216-4.
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    • Synthesis of novel coumarin containing conjugated fluorescent polymers by Suzuki cross-coupling reactions and their chemosensing studies for iron and mercury ions. Prabhas Bhaumick, Asim Jana, Lokman H. Choudhury, Polymer, 2021, 218, 123415. https://doi.org/10.1016/j.polymer.2021.123415.
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    • Hydrogen Peroxide-Mediated Rapid Room Temperature Metal-Free C(sp2)-H Thiocyanation of Amino Pyrazoles, Amino Uracils, and Enamines. Danish Ali, Anoop Kumar Panday, Lokman H. Choudhury, The Journal of Organic Chemistry, 2020, 85, 13610-13620.  https://doi.org/10.1021/acs.joc.0c01738
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    • Recent applications of thiourea-based organocatalysts in asymmetric multicomponent reactions (AMCRs), Tasneem Parvin, Rahul Yadav and Lokman H. Choudhury, Organic & Biomolecular Chemistry, 2020, 18, 5513-5532.https://doi.org/10.1039/D0OB00595A
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    • One-pot synthesis of pyrimidine linked naphthoquinone-fused pyrroles by iodine-mediated multicomponent reactions, Anoop Kumar Panday, Danish Ali and Lokman H. Choudhury, Organic & Biomolecular Chemistry, 2020, 18, 4997-5007.https://doi.org/10.1039/D0OB00591F
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    • Synthesis of styryl linked fused dihydropyridines by catalyst-free multicomponent reactions, Rahul Yadav, Tasneem Parvin, Anoop Kumar Panday and Lokman H. Choudhury, Molecular Diversity, 2020, Accepted Manuscript.
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    • Aroyl hydrazone with large Stokes shift as a fluorescent probe for detection of Cu2+ in pure aqueous medium and in vivo studies, Romi Dwivedi, Saumya Singh,, Brijesh Singh Chauhan, S.Srikrishna, Anoop Kumar Panday, Lokman H. Choudhury and Vinod Prasad Singh, Journal of Photochemistry and Photobiology A: Chemistry,2020, 395, 112501
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    • Microwave assisted synthesis of β-keto thioethers and furan derivatives by thiol directed multicomponent reactions, Asim Jana, Prabhas Bhaumick and Lokman H. Choudhury, New Journal of Chemistry,2020, 44, 8442-8453.
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    • Multicomponent synthesis of diphenyl 1, 3-thiazole-barbituric acid hybrids and their fluorescence property studies, Alok Mahata, Prabhas Bhaumick, Anoop K. Panday, Rahul Yadav, Tasneem Parvin and Lokman H. Choudhury, New Journal of Chemistry,2020,44, 4798-4811. DOI: 10.1039/D0NJ00406E
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    • Cs2CO3 mediated rapid room temperature synthesis of 3-amino-2-aroyl benzofurans and their copper catalyzed N-arylation reactions, Anoop Kumar Panday, Danish Ali and Lokman H. Choudhury,ACS Omega, 2020, 5, 3646-3660.https://doi.org/10.1021/acsomega.9b04169
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    • I2/DMSO mediated multicomponent reaction for the synthesis of 2-arylbenzo[d]imidazo[2,1-b] thiazole derivatives, Asim Jana, Prabhas Bhaumick, Anoop Kumar Panday, Richa Mishra and Lokman H. Choudhury, Organic & Biomolecular Chemistry, 2019, 17, 5316-5330.
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    • Synthesis of spirooxindoles fused with pyrazolo-tetrahydropyridinone and coumarin-dihydropyridine-pyrazole tetracycles by reaction medium dependent isatin-based multicomponent reactions. Richa Mishra, Asim Jana, Anoop Panday and Lokman H Choudhury, New Journal of Chemistry, 2019, 43, 2920-2932
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    • Synthesis of fused pyrroles containing 4-hydroxycoumarins by regioselective metal-free multicomponent reactions. Richa Mishra, Asim Jana, Anoop K. Panday and Lokman H. Choudhury, Organic & Biomolecular Chemistry, 2018, 16, 3289-3302.
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    • Lemon juice mediated multicomponent reactions for the synthesis of fused imidazoles, Argha Saha, Asim Jana and Lokman H. Choudhury, New Journal of Chemistry, 2018, 42, 17909-17922
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    • Synthesis of pyrimidine fused quinolines by ligand-free copper-catalyzed domino reactions. Anoop K. Panday, R. Mishra, A. Jana, T. Parvin and Lokman H. Choudhury, The Journal of Organic Chemistry 2018, 83, 3624-3632
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    • Recent advances of aminopyrimidines in multicomponent reactions, Ruchi Bharti, Pooja Kumari, Tasneem Parvin and Lokman H. Choudhury, Current Organic Chemistry, 2018, 22, 417-445. (Review article)
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    • Intracellular application and logic gate behavior of a ‘turn off-on-off’type probe for selective detection of Al 3+ and F− ions in pure aqueous medium. R. Dwivedi, D. P. Singh, B. S. Chauhan, S. Srikrishna, Anoop Kumar Panday, Lokman H Choudhury, V. P. Singh, Sensors and Actuators B: Chemical , 2018, 258, 881-894.
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    • Synthesis of thio and selenoethers of cyclic β‐hydroxy carbonyls and amino uracils: A metal‐free regioselective I2/DMSO mediated reaction. A. Jana, A.K. Panday, R. Mishra, T. Parvin, Lokman H. Choudhury, ChemistrySelect, 2017, 2, 9420-9424.
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    • Multicomponent reactions of arylglyoxal, 4‐hydroxycoumarin, and cyclic 1, 3‐C, N‐binucleophiles: binucleophile‐directed synthesis of fused five‐and six-membered N-heterocycles. R. Mishra, A.K. Panday, Lokman H. Choudhury, J Pal, R Subramanian, A Verma, European Journal of Organic Chemistry, 2017, 2789-2800.
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    • Synthesis of novel 5,6-disubstituted pyrrolo [2,3-d]pyrimidine-2,4-diones via one-pot three component reactions. Shaik Karamthulla, Asim Jana, and Lokman H. Choudhury, ACS Comb. Sci., 2017, 19,108-112.
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    • Molecular diversity from the three-component reaction of 2-hydroxy-1,4-naphthaquinone, aldehydes and 6-aminouracils: a reaction condition dependent MCR. R. Bharti, P. Kumari, Tasneem Parvin and Lokman H. Choudhury, RSC Adv., 2017, 7, 3928-3933.
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    • Catalyst-free microwave-assisted arylglyoxal-based multicomponent reactions for the synthesis of fused pyrans. Richa Mishra and Lokman H. Choudhury, RSC. Adv., 2016, 6, 24464-24469.
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    • Ultrasound assisted multicomponent reactions: a green method for the synthesis of highly functionalized selenopyridines using reusable polyethylene glycol as reaction medium. Md. Nasim Khan, Shaik Karamthulla, Lokman H. Choudhury and Md. S. H. Faizi, RSC Adv., 2015, 5, 22168-22172.
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    • Microwave-assisted synthesis of novel 2, 3-disubstituted imidazo[1,2-a]pyridines via one-pot three component reactions. Shaik Karamthulla, Md. Nasim Khan and Lokman H. Choudhury, RSC Adv., 2015, 5, 19724-19733.
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    • Synthesis of pyranocoumarin fused spirooxindoles via Knoevenagel/Michael/cyclization sequence: a regioselective organocatalyzed multicomponent reaction. Suman Pal, Md. Nasim Khan, Shaik Karamthulla and Lokman H. Choudhury, Tetrahedron Lett., 2015, 56, 359–364.
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    • On-water" synthesis of novel trisubstituted 1, 3-thiazoles via microwave-assisted catalyst-free domino reactions. Shaik Karamthulla, Suman Pal, Md Nasim Khan, and Lokman H. Choudhury, RSC Adv., 2014, 4, 37889-37899.
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    • Multicomponent reactions (MCRs) for the facile access of coumarin fused dihydroquinolines and quinolines: Synthesis and photophysical studies. Md Nasim Khan, Suman Pal, Shaik Karamthulla and Lokman H. Choudhury, New J. Chem., 2014,38, 4722-4729.
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    • Synthesis of pentasubstituted pyrroles via catalyst free multicomponent reactions. Shaik Karamthulla, Suman Pal, Md Nasim Khan, and Lokman H. Choudhury, Synlett, 2014, 25, 1926. (Highlighted in Synfacts, 2014,10(10),1031.)
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    • L-proline catalyzed multicomponent reactions:facile access to 2H-benzo[g]pyrazolo[3,4-b]-quinoline-5,10(4H,11H)-dione derivatives. Shaik Karamthulla, Suman Pal, Tasneem Parvin and Lokman H. Choudhury, RSC Adv., 2014, 4, 15319–15324.
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    • Imidazole as organocatalyst for multicomponent reactions: Diversity oriented synthesis of functionalized hetero and carbocycles using in situ-generated benzylidenemalononitrile derivatives. Md Nasim Khan, Suman Pal, Shaik Karamthulla and Lokman H. Choudhury, RSC Adv., 2014, 4, 3732-3741.
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    • One pot four-component reaction for the efficient synthesis of spiro[indoline-3,4'-pyrano [2,3 c]pyrazole]-3'-carboxylate derivatives. Suman Pal, Md. Nasim Khan, Shaik Karamthulla, Sk Jahir Abbas and Lokman H. Choudhury, Tetrahedron Lett., 2013, 54, 5434-5440.
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    • KF/Al2O3 mediated multicomponent reactions for the efficient synthesis of highly substituted dihydropyridines. Suman Pal, Md. Nasim Khan and Lokman H. Choudhury, J. Heterocyclic Chem., 2014, 51, E156-E162.
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    • Synthesis of novel spiro[indoline-3,79-pyrrolo[1,2-c]imidazole]-6¢-carbonitrile derivatives in water using a regioselective sequential three component reaction. Shaik Karamthulla, Suman Pal, Md. Nasim Khan and Lokman H. Choudhury, RSC Adv., 2013, 3, 15576-15581.
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    • Molecular iodine catalyzed one-pot multicomponent reactions for the synthesis of dihydrochromeno[4,3-b]pyrazolo[4,3-e]pyridin-6(7H)-ones. Suman Pal, Md. Nasim Khan, Shaik Karamthulla and Lokman H. Choudhury, RSC Adv., 2013, 3, 15705-15711.
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    • PEG-mediated one-pot multicomponent reactions for the efficient synthesis of functionalized dihydropyridines and their functional group dependent DNA cleavage activity. Suman Pal, Vandana Singh, Prolay Das, Lokman H Choudhury. Bioorganic Chemistry, 2013, 48, 8-15.
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    • One-pot multicomponent reactions for the efficient synthesis of highly functionalized dihydropyridines. Suman Pal, Lokman H. Choudhury and Tasneem Parvin, Synth. Comm., 2013, 43, 986–992.
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    • A simple and efficient method for the facile access of highly functionalized pyridines and their fluorescence property studies. Md. Nasim Khan, Suman Pal, Tasneem Parvin and Lokman H. Choudhury, RSC Adv., 2012, 2, 12305–12314.
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    • Recent advances in the chemistry of imine-based multicomponent reactions (MCRs). Lokman H. Choudhury and Tasneem Parvin, Tetrahedron , 2011, 67, 8213-8228.(Review article)
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    • VCl3 catalyzed imine-based multicomponent reactions for the facile access of functionalized tetrahydropyridines and β-amino carbonyls. Suman Pal, Lokman H. Choudhury and Tasneem Parvin, Mol. Divers., 2012, 16, 129-143.
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    • A stereoselective cyclisation cascade mediated by SmI2–H2O: synthetic studies towards stolonidiol. Thomas M. Baker, Lisa A. Sloan, Lokman H. Choudhury, Masahito Murai, David J. Procter, Tetrahedron: Asymmetry, 2010, 21, 1246-1261.
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    • Recent advances in the application of bromodimethylsulfonium bromide (BDMS) in organic synthesis. Lokman H. Choudhury, Tasneem Parvin and Abu. T. Khan, Tetrahedron , 2009, 65, 9513-9526.(Review article)
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    • A simple and convenient one-pot synthesis of benzimidazole derivatives using cobalt(II) chloride hexahydrate as catalyst. Abu T. Khan, Tasneem Parvin, and Lokman H. Choudhury, Synth. comm. 2009, 39, 2339-2346.
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    • Effects of substituents in the β-position of 1, 3-dicarbonyl compounds in Bromodimethylsulfonium bromide catalyzed multicomponent reactions: A facile access to functionalized piperidines. Abu T. Khan, Tasneem Parvin, and Lokman H. Choudhury, J. Org. Chem., 2008, 73, 8398–8402.
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    • Bromodimethylsulfonium bromide (BDMS) catalyzed three-component Mannich-type reaction. Abu T. Khan, Tasneem Parvin, and Lokman H. Choudhury, Eur. J. Org. Chem., 2008, 834-839.
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    • Bromodimethylsulfonium bromide mediated aza-Micheal addition of amines to electron deficient alkenes. Abu T. Khan, Tasneem Parvin, Sarifuddin Gazi and Lokman H. Choudhury, Tetrahedron Lett., 2007, 48, 3805-3808.
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    • Iron (III) chloride catalyzed convenient one-pot synthesis of β-acetamido carbonyl compounds. Abu T. Khan, Tasneem Parvin and Lokman H. Choudhury, Tetrahedron, 2007, 63, 5593-5601.
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    • A simple and convenient synthetic protocol for oxidation of alkyl arenes into ketones using aqueous hydrogen bromide/hydrogen peroxide. Abu T. Khan, Tasneem Parvin, Lokman H. Choudhury and Subrata Ghosh, Tetrahedron Lett., 2007, 48, 2271-2274.
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    • CeCl3.7H2O: An efficient and reusable catalyst for the preparation of β-acetamido carbonyl compounds by multi-component reactions (MCRs). Abu T. Khan, Lokman H. Choudhury, Tasneem Parvin and Md. Asif Ali, Tetrahedron Lett., 2006, 47, 8137-8141.
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    • A mild and highly regioselective method for α-bromination of β-keto esters and 1,3-diketones using bromodimethylsulfonium bromide (BDMS). Abu T. Khan, Md. Asif Ali, Papori Goswami and Lokman H. Choudhury, J.Org. Chem., 2006, 71, 8961-8963.
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    • Silica supported perchloric acid(HClO4-SiO2): A versatile catalyst for the tetrahydropyranylation, thioacetalization and oxathioacetalization. Abu T. Khan, Tasneem Parvin and Lokman H. Choudhury, Synthesis, 2006, 2497-2502.
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    • Bromodimethylsulfonium bromide: A versatile reagent in organic synthesis. Md. Lokman H. Choudhury, Synlett, Spotlight 2006, 1619.
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    • Silica supported perchloric acid (HClO4-SiO2): A highly efficient and reusable catalyst for geminal diacylation of aldehydes under solvent-free conditions. Abu T. Khan, Lokman H. Choudhury and Subrata Ghosh, Journal of Molecular Catalysis A: Chemical, 2006, 255, 230.
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    • A mild and environmentally acceptable synthetic protocol for chemoselective α-bromination of β-keto ester and 1,3-diketones. Abu T. Khan, Papori Goswami, and Lokman H. Choudhury, Tetrahedron Lett.,2006, 47, 2751-2754.
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    • Perchloric acid impregnated on silica gel (HClO4- SiO2): A versatile catalyst for Michael addition of thiols to the electron deficient alkenes. Abu T. Khan, Subrata Ghosh and Lokman H. Choudhury, Eur. J. Org. Chem., 2006, 2226-223.
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    • A Highly efficient synthetic protocol for tetrahydropyranylation/depyranylation of alcohols and phenols. Abu T. Khan, Subrata Ghosh and Lokman H. Choudhury, Eur. J. Org. Chem., 2005, 4891-4896.
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    • Acetonyltriphenylphosphonium bromide (ATPB): A versatile reagent for the acylation of alcohols, phenols, thiols, amines and for 1, 1-diacylation of aldehydes under solvent-free conditions. Abu T. Khan, Lokman H. Choudhury and Subrata Ghosh, Eur. J. Org. Chem., 2005, 2782-2787.
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    • A catalytic amount of nickel (II) chloride hexahydrate and 1, 2- ethanedithiol is a good combination for the cleavage of tetrahydropyranyl (THP) and tert-butyldimethylsilyl (TBS) ethers. Abu T. Khan, Samimul Islam, Lokman H. Choudhury and Subrata Ghosh, Tetrahedron Lett., 2004, 45, 9617-962.
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    • Cupric sulfate pentahydrate (CuSO4.5H2O): A mild and efficient catalyst for tetrahydropyranylation /depyranylation of alcohols and phenols. Abu T. Khan, Lokman H. Choudhury and Subrata Ghosh,Tetrahedron Lett., 2004, 45, 7891-7894.
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    • A simple and useful synthetic protocol for selective deprotection of tert -butyldimethylsilyl (TBS) ethers.Abu T. Khan, Subrata Ghosh and Lokman H. Choudhury, Eur. J. Org. Chem., 2004, 2198-2204.
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